Two studies examined associations between college students' help seeking and perceptions of their classes' achievement goal structure. Study 1 established that students' help seeking (N = 883 in 6 chemistry classes) could be parsimoniously described by distinct approach (intentions to seek autonomous help from teachers) and avoidance patterns (threat, avoidance intentions, seeking expedient help). In Study 2, after controlling for students' personal achievement goal orientations (N = 852 in 13 psychology classes), within-class differences in perceived class emphasis on mastery positively predicted help-seeking approach and negatively predicted help-seeking avoidance patterns, whereas perceived class emphasis on performance-avoid goals positively predicted help-seeking avoidance. Students in classes with greater perceived emphasis on performance-avoid goals had higher levels of help-seeking avoidance patterns. Results complement previous research on help seeking and achievement goals with younger learners and provide support for the role of classroom achievement goal structure in student motivation and performance.