Since 1975, the Monitoring the Future project has provided the nation with an important window through which to view the rapidly changing problems of drug use among American youth. This latest two-volume monograph reports the results of the twenty-seventh (2001) national survey of drug use and related attitudes and beliefs among American high school seniors. Results from the secondary school samples of eighth, tenth, and twelfth graders are contained in Volume I. It reports the results of the national survey of drug use and related attitudes and beliefs among 8th, 10th, and 12th graders. Distinctions are made among important demographic subgroups in these populations based on gender, college plans, region of the country, population density, parents' education, and race and ethnicity. Following the introductory chapter, chapter 2 presents key findings. Study design is reviewed in chapter 3. Chapters 4 and 5 explain the prevalence and trends in drug use. Chapter 6 discusses the initiation rates by grade level. Chapter 7 explains the degree and duration of drug highs. Chapter 8 discusses attitudes about drug use, and chapter 9 reviews the social milieu. Chapter 10 sums up other findings from the study. Volume 1 was preceded by an advance summary publication of its key findings. (Contains 5 appendixes, 128 tables, and 94 figures.) (GCP)