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Quantitative Analysis of Agrammatism in Agrammatic Primary Progressive Aphasia and Dominant Apraxia of Speech
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Tetzloff, Katerina A.; Utianski, Rene L.; Duffy, Joseph R.; Clark, Heather M.; Strand, Edythe A.; Josephs, Keith A.; Whitwell, Jennifer L. – Journal of Speech, Language, and Hearing Research, 2018
Purpose: The aims of the study were to assess and compare grammatical deficits in written and spoken language production in subjects with agrammatic primary progressive aphasia (agPPA) and in subjects with agrammatism in the context of dominant apraxia of speech (DAOS) and to investigate neuroanatomical correlates. Method: Eight agPPA and 21 DAOS…
Descriptors: Aphasia, Speech Impairments, Correlation, Comparative Analysis
A Longitudinal Evaluation of Speech Rate in Primary Progressive Apraxia of Speech
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Utianski, Rene L.; Martin, Peter R.; Hanley, Holly; Duffy, Joseph R.; Botha, Hugo; Clark, Heather M.; Whitwell, Jennifer L.; Josephs, Keith A. – Journal of Speech, Language, and Hearing Research, 2021
Purpose: Individuals with primary progressive apraxia of speech (PPAOS) have apraxia of speech (AOS) in which disruptions in articulation or prosody predominate the speech pattern, referred to, respectively, as phonetic or prosodic subtypes. Many develop aphasia and/or dysarthria. Past research has demonstrated that simple temporal acoustic…
Descriptors: Speech Communication, Longitudinal Studies, Articulation (Speech), Intonation
The Diagnosis and Understanding of Apraxia of Speech: Why Including Neurodegenerative Etiologies May Be Important
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Duffy, Joseph R.; Josephs, Keith A. – Journal of Speech, Language, and Hearing Research, 2012
Purpose: To discuss apraxia of speech (AOS) as it occurs in neurodegenerative disease (progressive AOS [PAOS]) and how its careful study may contribute to general concepts of AOS and help refine its diagnostic criteria. Method: The article summarizes our current understanding of the clinical features and neuroanatomical and pathologic correlates…
Descriptors: Neurological Impairments, Speech Impairments, Clinical Diagnosis, Etiology
Progressive Apraxia of Speech as a Sign of Motor Neuron Disease
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Duffy, Joseph R.; Peach, Richard K.; Strand, Edythe A. – American Journal of Speech-Language Pathology, 2007
Purpose: To document and describe in detail the occurrence of apraxia of speech (AOS) in a group of individuals with a diagnosis of motor neuron disease (MND). Method: Seven individuals with MND and AOS were identified from among 80 patients with a variety of neurodegenerative diseases and AOS (J. R. Duffy, 2006). The history, presenting…
Descriptors: Speech Impairments, Neurological Impairments, Psychomotor Skills, Physical Disabilities
Parametric Quantitative Acoustic Analysis of Conversation Produced by Speakers with Dysarthria and Healthy Speakers
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Rosen, Kristin M.; Kent, Raymond D.; Delaney, Amy L.; Duffy, Joseph R. – Journal of Speech, Language, and Hearing Research, 2006
Purpose: This study's main purpose was to (a) identify acoustic signatures of hypokinetic dysarthria (HKD) that are robust to phonetic variation in conversational speech and (b) determine specific characteristics of the variability associated with HKD. Method: Twenty healthy control (HC) participants and 20 participants with HKD associated with…
Descriptors: Acoustics, Speech Impairments, Neurological Impairments, Comparative Analysis
Speech and Language Findings Associated with Paraneoplastic Cerebellar Degeneration
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Paslawski, Teresa; Duffy, Joseph R.; Vernino, Steven – American Journal of Speech-Language Pathology, 2005
Paraneoplastic cerebellar degeneration (PCD) is an autoimmune disease that can be associated with cancer of the breast, lung, and ovary. The clinical presentation of PCD commonly includes ataxia, visual disturbances, and dysarthria. The speech disturbances associated with PCD have not been well characterized, despite general acceptance that…
Descriptors: Neurological Impairments, Cancer, Patients, Speech Impairments