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Weible, Aldis P.; Oh, M. Matthew; Lee, Grace; Disterhoft, John F. – Learning & Memory, 2004
Cholinergic systems are critical to the neural mechanisms mediating learning. Reduced nicotinic cholinergic receptor (nAChR) binding is a hallmark of normal aging. These reductions are markedly more severe in some dementias, such as Alzheimer's disease. Pharmacological central nervous system therapies are a means to ameliorate the cognitive…
Descriptors: Conditioning, Animals, Eye Movements, Pharmacology