The communicative relationships between scientists and audiences they address beyond their specialized fields have become increasingly strained. These fractures result not simply from an ill-informed lay public, but from deeper trepidation about the ethos of science. This forum offers three distinct, yet intertwined, interdisciplinary perspectives on how communication centers can enhance science communication. Part I engages with science communication from the administrative perspective of the communication center director. This section highlights how the synergies between communication centers and the sciences can entrench a center's role as an indispensable resource for preparing scientists to address audiences of nonspecialists. The author offers fruitful suggestions for communication centers encouraging scientific communicators to engage with their publics rather than dictate recommendations and report findings to them. Part II voices the views of a scientist who distills the ways commonly taught communication skills apply to scientific communication. The author explains--and the section embodies--some of the specific communicative practices that best serve scientists as they attempt to relate to diverse audiences. The section concludes by stressing the importance of storytelling that enables scientists to offer compelling accounts of their research and rationales for its support. Invoking the perspective of science and technology studies, in Part III, the author reflects on how to bridge epistemological divides that often lead to confrontational relationships between scientists and non-scientists. Working with both scientific communicators and lay audiences in joint endeavors, communication centers can develop mutual respect and restore trust in the institution of science.