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Siegel, Lianne; Chu, Haitao – Research Synthesis Methods, 2023
Reference intervals, or reference ranges, aid medical decision-making by containing a pre-specified proportion (e.g., 95%) of the measurements in a representative healthy population. We recently proposed three approaches for estimating a reference interval from a meta-analysis based on a random effects model: a frequentist approach, a Bayesian…
Descriptors: Bayesian Statistics, Meta Analysis, Intervals, Decision Making
Hong, Hwanhee; Chu, Haitao; Zhang, Jing; Carlin, Bradley P. – Research Synthesis Methods, 2016
Bayesian statistical approaches to mixed treatment comparisons (MTCs) are becoming more popular because of their flexibility and interpretability. Many randomized clinical trials report multiple outcomes with possible inherent correlations. Moreover, MTC data are typically sparse (although richer than standard meta-analysis, comparing only two…
Descriptors: Bayesian Statistics, Meta Analysis, Outcomes of Treatment, Comparative Analysis