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The Spectrum of Disease in Chronic Traumatic Encephalopathy
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McKee, Ann C.; Stein, Thor D.; Nowinski, Christopher J.; Stern, Robert A.; Daneshvar, Daniel H.; Alvarez, Victor E.; Lee, Hyo-Soon; Hall, Garth; Wojtowicz, Sydney M.; Baugh, Christine M.; Riley, David O.; Kubilus, Caroline A.; Cormier, Kerry A.; Jacobs, Matthew A.; Martin, Brett R.; Abraham, Carmela R.; Ikezu, Tsuneya; Reichard, Robert Ross; Wolozin, Benjamin L.; Budson, Andrew E.; Goldstein, Lee E.; Kowall, Neil W.; Cantu, Robert C. – Brain, 2013
Chronic traumatic encephalopathy is a progressive tauopathy that occurs as a consequence of repetitive mild traumatic brain injury. We analysed post-mortem brains obtained from a cohort of 85 subjects with histories of repetitive mild traumatic brain injury and found evidence of chronic traumatic encephalopathy in 68 subjects: all males, ranging…
Descriptors: Neurological Impairments, Head Injuries, Chronic Illness, Brain
An Evaluation of Recollection and Familiarity in Alzheimer's Disease and Mild Cognitive Impairment Using Receiver Operating Characteristics
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Ally, Brandon A.; Gold, Carl A.; Budson, Andrew E. – Brain and Cognition, 2009
There is a need to investigate exactly how memory breaks down in the course of Alzheimer's disease (AD). Examining what aspects of memorial processing remain relatively intact early in the disease process will allow us to develop behavioral interventions and possible drug therapies focused on these intact processes. Several recent studies have…
Descriptors: Alzheimers Disease, Recall (Psychology), Familiarity, Patients
Preserved Metamemorial Ability in Patients with Mild Alzheimer's Disease: Shifting Response Bias
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Waring, Jill D.; Chong, Hyemi; Wolk, David A.; Budson, Andrew E. – Brain and Cognition, 2008
Patients with mild Alzheimer's disease (AD) display a greater tendency to endorse unstudied items as "old" on memory tests than healthy older adults. This liberal response bias may result in mistaken beliefs about the completion of common tasks. This research attempted to determine whether it was possible to shift the response bias of mild AD…
Descriptors: Response Style (Tests), Alzheimers Disease, Patients, Recognition (Psychology)