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Using PyMOL to Explore the Effects of ph on Noncovalent Interactions between Immunoglobulin G and Protein A: A Guided-Inquiry Biochemistry Activity
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Roche Allred, Zahilyn D.; Tai, Heeyoung; Bretz, Stacey Lowery; Page, Richard C. – Biochemistry and Molecular Biology Education, 2017
Students' understandings of foundational concepts such as noncovalent interactions, pH and pK[subscript a] are crucial for success in undergraduate biochemistry courses. We developed a guided-inquiry activity to aid students in making connections between noncovalent interactions and pH/pK[subscript a]. Students explore these concepts by examining…
Descriptors: Biochemistry, Science Instruction, Undergraduate Students, Interaction
A Guided Inquiry Experiment for the Measurement of Activation Energies in the Biophysical Chemistry Laboratory: Decarboxylation of Pyrrole-2-Carboxylate
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Hutchinson, Kelly M.; Bretz, Stacey Lowery; Mettee, Howard D.; Smiley, Jeffrey A. – Biochemistry and Molecular Biology Education, 2005
A laboratory experiment for undergraduate biophysical chemistry is described, in which the acid concentration and temperature dependences of the decarboxylation of pyrrole-2-carboxylate are measured using a continuous ultraviolet (UV) spectrophotometric assay. Data collection and analysis are structured using principles of guided inquiry. Data…
Descriptors: Laboratory Experiments, Chemistry, College Science, Undergraduate Students