Mounting evidence indicates a dispositional component to global job satisfaction. Unfortunately, however, relatively little attention has been given to the potential effects of dispositions on work-related attitudes other than global job satisfaction. We used a five-year prospective design to investigate the relationships of affective disposition with a set of attitudes oriented toward different aspects of work: the job, the organization, and the career. Job satisfaction, organizational commitment, job involvement, career commitment and career satisfaction each showed significant stability over five years. Cross-lagged panel analyses suggested that affective disposition plays an important role in the change of job attitudes across time. Analyses also support the hypothesis that affective disposition would be more weakly related to job involvement than to the other attitudes.