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| Learning & Memory | 2 |
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Direct linkJami, Shekib; Barad, Mark; Cain, Christopher K.; Godsil, Bill P. – Learning & Memory, 2005
We recently reported that fear extinction, a form of inhibitory learning, is selectively blocked by systemic administration of L-type voltage-gated calcium channel (LVGCC) antagonists, including nifedipine, in mice. We here replicate this finding and examine three reduced contingency effects after vehicle or nifedipine (40 mg/kg) administration.…
Descriptors: Inhibition, Animals, Contingency Management, Behavior Modification
Ponnusamy, Ravikumar; Nissim, Helen A.; Barad, Mark – Learning & Memory, 2005
Extinction of conditioned fear in animals is the explicit model of behavior therapy for human anxiety disorders, including panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder. Based on previous data indicating that fear extinction in rats is blocked by quinpirole, an agonist of dopamine D2 receptors, we hypothesized…
Descriptors: Memory, Behavior Modification, Fear, Anxiety
