According to current estimates, more than a quarter of all students and over 40 percent of African American and Hispanic students do not graduate from high school on time. The vast majority of those young people who do not graduate with their peers drop out. The enormous costs to these individuals, their communities, and our society require us to invest in systems that accurately identify young people at risk of dropping out and provide the supports necessary to keep them on track to graduation. This chapter offers a framework for action that calls on communities to identify the scale and scope of the dropout problem and understand why students disengage from school; transform or replace low-performing schools; install early warning and multitiered response systems that provide comprehensive, targeted, and intensive supports to students in and out of school; establish supportive policies and resource allocations; and build community will and capacity so positive changes are deeply implemented and sustained. (Contains 23 notes and 1 figure.)