Each year since 1975, about 17,000 seniors have participated in a national survey conducted in some 130 high schools to assess students' changing lifestyles, values, and preferences. This publication is one in a series of annual monographs to disseminate many of the epidemiological findings from the study. It reports the results of the national survey of drug use and related attitudes and beliefs among 8th, 10th, and 12th graders. Distinctions are made among important demographic subgroups in these populations based on gender, college plans, region of the country, population density, parents' education, and race and ethnicity. Following the introductory chapter, chapter 2 presents key findings. Study design is reviewed in chapter 3. Chapters 4 and 5 explain the prevalence and trends in drug use. Chapter 6 discusses the initiation rates by grade level. Chapter 7 explains the degree and duration of drug highs. Chapter 8 discusses attitudes about drug use, and chapter 9 reviews the social milieu. Chapter 10 sums up other findings from the study. Volume 1 was preceded by an advance summary publication of its key findings. (Contains 5 appendixes, 146 tables and 103 figures.) (JDM)