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Watts, Christopher R.; Awan, Shaheen N.; Marler, Jeffrey A. – Clinical Linguistics & Phonetics, 2008
The human elastin gene (ELN) is responsible for the generation of elastic fibres in the extracellular matrix of connective tissue throughout the body, including the vocal folds. Individuals with Supravalvular aortic stenosis (SVAS) and Williams syndrome (WS) lack one normal ELN allele due to heterozygous ELN abnormalities, resulting in a…
Descriptors: Biomechanics, Acoustics, Genetics, Cytology
Awan, Shaheen N.; Roy, Nelson – Clinical Linguistics & Phonetics, 2006
During assessment and management of individuals with voice disorders, clinicians routinely attempt to describe or quantify the severity of a patient's dysphonia. This investigation used acoustic measures derived from sustained vowel samples to predict dysphonia severity (as determined by auditory-perceptual ratings), for a diverse set of voice…
Descriptors: Severity (of Disability), Prediction, Multiple Regression Analysis, Acoustics