Peer relationships play an important role in socialization during childhood and young adolescence. Negative relationships may pose multiple difficulties for children related to their development that can have lifelong influences. Research indicates that the quality of peer relationships is associated with a variety of outcomes, such as social adjustment in school; academic performance; and general self-regard. Among a number of influential factors, temperament was found to be a major factor in building peer relationships. Positive temperament patterns account for the frequency of peer interactions. In the classroom setting, teachers encounter children with different levels of temperament. To be a "guide by the side" rather than a "sage on the stage," teachers need to adopt effective strategies and provide an environment that matches each individual's ways of learning. Some useful suggestions for teachers are included in this article.