This study focuses on developing specific vocabulary learning strategies to assist the receptive knowledge of English for Specific Purposes (ESP). It aims to provide a practical framework for teaching technical vocabulary. The study introduced the Multimedia Strategic Vocabulary Learning (MSVL) model and investigated its effects on teaching technical vocabulary to pre-engineering students in online courses during the early wave of COVID-19. A total of 88 Saudi undergraduate students randomly assigned to control and experimental groups were treated with an intact pre-engineering ESP course for ten weeks. Vocabulary learning strategies from Schmitt's (1997) vocabulary taxonomy were adopted and incorporated into two stages of the vocabulary acquisition process. The experimental group was treated with the MSVL model through multimedia and explicit vocabulary learning instructions in online classes using Blackboard Learning Management System (LMS) to assist them with specialized vocabulary acquisition. The dependent measure in this study was the participants' receptive knowledge of technical vocabulary, which was assessed using the pre-test, post-test, and delayed post-test. The findings indicated that using the MSVL model significantly improved the experimental group's receptive knowledge of technical vocabulary. This study's guidelines help educators create multimedia resources for ESP learners, preparing them for their professions.