Data suggest that acquaintance and date rape may account for 50-70 percent of all reported rapes in the United States. Recent findings also indicate that one in four college women have been raped or a victim of attempted rape. As most rape victims are between 15 and 24 years of age, high school-based education programs must be provided if society expects to eliminate this social and public health problem. A series of lessons are proposed that can be included as part of a high school safety and injury prevention unit in an existing health education curriculum. This concept-based unit includes well defined behavioral objectives, recommended content, suggested materials and resources, suggested learning activities, and evaluation measures. Content includes: types of rape; relevant epidemiologic data; myths and stereotypes about rape; cultural influences and risk-factors associated with rape (including alcohol and drug abuse); verbal and non-verbal communication; and preventive strategies. Activities are designed to increase knowledge; to help students examine personal beliefs and cultural attitudes; and to strengthen communication, decision-making, and assertive-resistance skills. Students learn to recognize at-risk situations, verbal and nonverbal messages and stages that commonly occur prior to an acquaintance/date rape. Also, students practice prevention strategies and discuss how to apply them to everyday life. Instructional methods include lecture/discussion, video, group activities, attitudinal inventories, critical incidents, and music. Suggestions for student evaluation are provided. Appendixes contain definitions, sexual assertiveness continuum, text of three popular songs, scenarios, sexual assault/sexual behavior questionnaire, a list of prevention strategies, and practical tips. (Author/JB)