Kids are drawn to dolls and dump trucks, and crashing the two together might just be a child's favorite pastime. Who knew such a simple pleasure could serve as an accessible, compelling phenomenon for instigating investigations of force and motion. With a few inexpensive materials straight out of the toy box (literally, a doll, a dump truck, a…

We here propose a simple and fast hands-on activity requiring limited equipment, to introduce students of various levels (bachelor's or high school) and backgrounds (from science to arts) to the chemistry of color. The different colors of stained glass are replicated through the deposition, on ordinary glass slides, of silica coatings colored by…

It may be asserted that there is no more effective deterrent to crime than the certainty of detection. Equally true is that there is no surer way to establishing identity than by fingerprints. The detection of fingerprints at the scene of crime is therefore one of the most powerful tools available in casework investigations. However, if the crime…

Electrophoresis is integral to analytical and biochemistry experiences in undergraduate education; however, fundamental principles of the method are often taught in upper-level laboratories through hands-on experiences. A laboratory activity is reported that teaches the concepts of electrophoretic mobility and electroosmotic flow. A single…

During the unprecedented and rapid spread of the coronavirus disease-2019 (COVID-19) around the World, students have been concerned about the disease as much as the rest of the global community. As a real-world problem, the COVID-19 pandemic with many different debatable facets has social and scientific components, impacts society, and shows…

Children can see the Moon with the naked eye and often are curious about the Moon and other objects in the sky, like the Sun and the stars. However, there is sometimes disagreement in early childhood about whether studying space is appropriate for young children. This activities described in this article engaged children who had different learning…

Electrophilic aromatic substitution (EAS) represents an important class of reactions taught in the undergraduate organic chemistry curriculum. The EAS reaction of benzene and its substituted derivatives is generally described as proceeding through a carbocation (arenium cation) intermediate, and the regiochemistry of the product is heavily…

Sanger sequencing, also known as dideoxy sequencing, is a widely used method for DNA sequencing, particularly for cloned plasmids and clinical samples. This technique requires a combination of essential biochemistry skills, such as a chain-termination reaction, gel electrophoresis, and fluorescence detection. Unfortunately, there is a lack of…

Previous articles in "Primary Science" have presented a range of ways to teach electricity in engaging and informative ways (e.g. Buckley and Harvey, 2014; Chapman, 2014; Norman, 2014; CLEAPSS, 2016) and Frank Harris provides an interesting historical account of the development and use of batteries in "School Science Review"…

Computational chemistry techniques are used along with spectroscopy to characterize acetaminophen synthesized in an undergraduate chemistry laboratory experiment. The inclusion of electronic structure calculations to provide infrared and Raman spectra in the synthesis and characterization of acetaminophen connects over-the-counter medications with…

The "Next Generation Science Standards" (NGSS) encourages educators to help kindergarteners formalize a big idea in physics: A push or pull can cause an object to begin moving, speed up, slow down, stop, or change the direction it is going (NGSS Lead States 2013). In this article, the authors share an exciting, classroom-tested…

Student feedback from an undergraduate biochemistry lab course suggested the use of visibly traceable proteins may assist learning. Based on this feedback, we used guided inquiry lab exercises where students developed and characterized a suite of fluorescent protein-dihydrofolate reductase (DHFR) fusions as tools for a biochemistry teaching lab.…

An inexpensive at-home quantitative analysis activity was developed for the determination of glucose in unknown samples using paper-based microfluidic devices. All of the materials and reagents for the activity fit in a small kit that was mailed to students. The only items students needed to supply were water and a smartphone. Microgram quantities…

One of the objectives in the science National Curriculum in England is to 'observe changes across the four seasons' (DfE, 2013: 9). The winter months can be a busy time for teachers, but can also cater for a wide range of science experiments based around the season. Practical investigations based on winter themes can hold a sense of magic and…

Enzyme-Linked Immunosorbent Assay (ELISA) is a versatile and widely used technique to detect and quantify small molecules in various clinical and analytical applications. It is also an effective tool for demonstrating the specificity between antibody and antigen to students across diverse disciplines. However, undergraduate laboratories often face…