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Protein Identification by Database Searching of Mass Spectrometry Data in the Teaching of Proteomics
Marquioni, Vinícius; Nunes, Francis Morais Franco; Novo-Mansur, Maria Teresa Marques – Journal of Chemical Education, 2021
Mass spectrometry is essential for large-scale protein identification in proteomics. By database searching of mass spectrometry data, it is possible to identify proteins without the need to interpret MS/MS spectra (de novo sequencing), which is time-consuming and not feasible as a systematic tool in proteomic analysis. Many authors have reported…
Descriptors: Spectroscopy, Biochemistry, Databases, Science Instruction