Disrupting a gene to determine its effect on an organism's phenotype is an indispensable tool in molecular biology. Such techniques are critical for understanding how a gene product contributes to the development and cellular identity of organisms. The explosion of genomic sequencing technologies combined with recent advances in genome-editing…

This chapter examines the core analytic elements of randomized experiments for social research. Its goal is to provide a compact discussion for faculty members, graduate students, and applied researchers of the design and analysis of randomized experiments for measuring the impacts of social or educational interventions. Design issues considered…

An oil spill occurs somewhere in the world almost every day of the year, and the consequences can be devastating. In this month's column, students explore the effects of oil spills on plants, animals, and the environment and investigate oil spill clean-up methods through a simulated oil spill. The activities described in this article give students…

Reviews literature on chromatography examining: books, reviews, student experiments; chromatographic systems, techniques, apparatus; detecting and identification of separated zones; preparative chromatography and radiochromatography; and applications related to specific materials (such as acids, alcohols, amino acids, antibiotics, enzymes, dyes,…

Experimental studies conducted since 1980 were reviewed. Each of the 34 studies concerning problem solving is briefly summarized, followed by comments, criticisms, and/or concerns. A summary indicates that experimental research of the 1980s seems to focus on: (1) children's processes, understanding, functioning, difficulties, and representations;…

Discusses the use of direct demonstration of the connections among the science process skills and the content areas of science. (MKR)

Describes problems in teaching problem solving and summarizes research in this area. Presents Guided Design or Guided Decision Making as a problem-solving approach in which groups of students work their way through a model of the problem-solving process as they wrestle with a discipline-specific situation. (PR)

Reviews the work of the Commission on Undergraduate Education in the Biological Sciences (CUEBS) from 1964 to 1972. Suggests that now is the appropriate time to reassess their efforts, to build on their successes, and to use their experience to attack some of the continuing problems facing biology education. (21 references) (KR)

This monograph discusses the current practices associated with the conduct of a research and experimentation program in technology education. It describes the background and bases of the program, the role of the teacher of research and experimentation, and advantages of the program. Next, the environment of the program is addressed, including the…

This ERIC Digest presents a brief description of some applications and findings of the microcomputer in science classrooms. It is suggested that microcomputer simulations are at least as effective as hands-on experiences for some cognitive outcomes and may in fact enhance these outcomes when the simulations are sequenced to follow hands-on…