The evolution of artificial intelligence (AI) presents an unprecedented opportunity for Historically Black Colleges and Universities (HBCUs) to lead in an era characterized by rapid technological advancement and societal transformation. This report explores the integral role HBCUs--with their history of academic excellence and commitment to inclusivity--can play in steering the AI revolution, ensuring that the Black community remains at the forefront of educational, economic, and social progress. Institutional leaders, faculty and instructors, and instructional support staff can benefit from the findings of this report, which is presented in the following sections: (1) Why AI Matters and the Unique Role of HBCUs in the AI Revolution; (2) An AI Policy and Practice Framework for Institutional Development; (3) AI and Curricular Innovation; (4) The Importance of Industry Partnerships and Student Development; and (5) AI at HBCUs: A Path to the Future. [This report was created in collaboration with the Thurgood Marshall College Fund.]