This guidance provides support for the use of artificial intelligence (AI) across various roles in West Virginia PK-12 schools, catering to the needs of superintendents, district staff, educators, and support staff. The guidance intends to focus on effectively and safely integrating AI, especially generative AI technologies, in classroom instruction, school administration, and district operations, while aligning with existing West Virginia Board of Education (WVBE) policies. Additionally, recognizing the need for ongoing support, the West Virginia Department of Education (WVDE) has developed a Canvas resource site, a hub of materials and resources for county school districts and educators. This site will be regularly updated alongside this guidance to ensure it remains a relevant and valuable resource.