This manual was written specifically to help school nurses conduct screenings for Usher syndrome, a genetic condition that involves deafness or hearing loss and the progressive loss of vision. It provides information on the step-by-step process of how to conduct a screening, the actual forms needed for a screening, and resources for referring students for further evaluations and counseling. Sections of the manual address: (1) symptoms of Usher syndrome; (2) heredity of the disorder; (3) how a screening is conducted; (4) conducting a paper screening; (5) station screening, the role of the screener, and the role of the interpreter; (6) evaluating the results; (7) when to recheck a student; and (8) when to refer a student for an opthalmological evaluation. Written and visual resources are provided, along with national, state, and regional organizations relating to Usher syndrome. Appendices include supplemental materials that address retinitis pigmentosa, characteristics of Usher syndrome and sensorineural hearing loss, electroretinogram evaluations, an Usher screening inservice agenda, and how to explain Usher syndrome to kids. A case study of a student with Usher syndrome is provided, and blank forms include questionnaires, the Cone Adaptation Test, the Field Screening Test and the Balance Test. (Contains 32 references.) (CR)