The U.S. Department of Education (ED) wishes to remind states, districts, schools, students, staff, families, and guardians as well as communities about the importance of: (1) addressing the prevention of infectious disease in schools, including the seasonal flu, viral meningitis, enterovirus, and Ebola; and (2) ensuring the continuity of teaching and learning in the event of student absences or school dismissals. The purpose of this document, therefore, is to provide recommendations to help schools maintain the continuity of teaching and learning for: (1) individuals or small groups of students who are out of school for extended periods; and (2) large groups of students and staff disrupted by school dismissals or large numbers of faculty absences. These recommendations present points for education stakeholders to consider as they plan for and improve their ability to provide continuous learning, ranging from take-home assignments to online learning initiatives. This document offers key questions for states, districts, school leaders, teachers, parents, and students to think through as they prepare for continuity of teaching and learning, and provides information on resource opportunities and best practices. Continuity of Teaching and Learning--Decision Table is appended.