Discusses some of the worldwide problems associated with the acquired immunodeficiency syndrome (AIDS) and infection with the human immunodeficiency virus type 1 (HIV-1). Calls for programs for the prevention and control of AIDS as an immediate priority in all countries. (TW)

Reports that by the end of 1987, nearly 50,000 cases of acquired immune deficiency syndrome (AIDS) had been reported in the United States since 1981, with 20,745 in 1987 alone. Discusses the disordinate proportion of cases involving black and Hispanic adults and children. (TW)

Followed eight male smokers with chronic pulmonary or cardiac disease through a smoking cessation program of gradual nicotine withdrawal, self-management, and relapse prevention. At one year, half remained abstinent, while relapsers smoked substantially less than before treatment. Reductions in carbon monoxide and thiocyanate levels were…

The feeding skills of 73 adults with severe developmental disabilities who aspirated were examined. Mobility, level of mental retardation, or feeding skill did not discriminate those who aspirated. Mealtime respiratory distress (65%) or chronic lung disease (55%), however, were significantly associated with aspiration. (Author/DB)

With few exceptions, the dynamics underlying the mood structures of individuals with Parkinson's Disease have consistently been overlooked. Based on 12 participants' daily self-reports over 72 days, we identified 10 participants whose covariance matrices for positive and negative affect were similar enough to warrant pooling. Dynamic factor models…

Discusses the complicated infection of human immunodeficiency virus type 1 (HIV-1) in its late stages of the acquired immune deficiency syndrome (AIDS) dementia complex. Explains the syndrome's development of abnormalities in cognition, motor performance, and behavior. (TW)

Poses questions about how we can control the acquired immune deficiency syndrome (AIDS) epidemic and the harm that it causes without unjustly discriminating against particular social groups and without unnecessarily infringing on the freedom of individuals. (TW)

All chronic illnesses represent assaults on multiple areas of functioning, not just the body. To examine the association between painful chronic illnesses and depression from a cognitive-behavioral perspective, 100 patients of the Pain Management Program at the West Haven, Connecticut Veterans Administration Hospital (78% males) completed a…

Reviews much of what is known about microtubules, which are biopolymers consisting predominantly of subunits of the globular protein, tubulin. Describes the functions of microtubules, their structure and assembly, microtube associated proteins, and microtubule-disrupting agents. (TW)

This study was conducted to identify information about Acquired Immune Deficiency Syndrome (AIDS) that educators should know to effectively teach about the disease in the classroom. The references identified were divided into seven major categories: (1) current scientific research concerned with the virus that causes AIDS; (2) the effects of the…

Comparison of adaptive skills of 2,144 adult individuals with Down's syndrome with other developmentally disabled persons found age-related deficits only in persons with Down's syndrome over 50 years of age. Findings supported an increased risk for Alzheimer's disease in persons with Down's syndrome, but with signs appearing later than previously…

ApoE gene polymorphism was examined in 100 adults with Down syndrome with and without dementia (Alzheimer's disease) and 346 control subjects. Additionally, a meta analysis of studies (total N=480 subjects) was performed. Results indicated a similar incidence of the gene across groups but subjects with the allele tended to an earlier onset of…

Comparison of cognitive processes in 23 individuals with Down's syndrome (DS) and 23 individuals of comparable mental handicap without Down's syndrome found that older (above 40 years) DS subjects had significantly poorer outcomes. The areas of speech rate, number finding, and expressive attention appeared to show the earliest signs of dementia of…

The importance of targeting certain stages in the life cycle of the virus for antiviral therapy is discussed with reference to the Human Immunodeficiency Virus type 1. Research conducted on a core antigen, p24, is described. (MSE)

Eight mothers with their 3.1- to 5.7-year-old hemophiliac children and eight control mothers with their nonhemophiliac children were videotaped while playing two games without tools and three additional games involving use of a knife, a pair of scissors, and a wooden hammer. Mothers of hemophiliac children did not correct their children when they…