There is a growing acknowledgment of the relationship between students' psychological well-being and educational success. However, relatively few studies have focused on a connection between the psychological well-being of students who have high abilities and their school ecology. School-based experiences associated with interactions involving students, individual characteristics, contextual aspects and time-related factors are explored as they relate to the psychological well-being of students with high abilities. Psychological well-being in this article refers to students' motivation, ability to cope with stressors, their expectations for the future, their involvement in the community, and their sense of life satisfaction. This position paper invites researchers, educators, and other school-based stakeholders to consider the importance of the interplay between students' psychological well-being and the ecology in which they work.