Research supports the premise that various mathematical topics can be categorized as being performed better by the left or right brain hemisphere. Hemispheric lateralization is defined as a learner's preferred hemisphere of control. Torrence's "Human Information Processing Survey" was given to 170 black female college students enrolled in Precalculus I (college algebra), Precalculus II (trigonometry, vectors, conics, and complex numbers), or Analysis I (beginning calculus for mathematics/science majors) to measure lateralization preference. Overall course grade was used to measure mathematical success/failure. Using a dichotomous left/right lateralization classification, descriptive statistics indicated that successful Precalculus I students were usually left dominant while unsuccessful students were usually right dominant. Successful Precalculus II students tended to be right dominant, while unsuccessful students were usually left dominant. No lateralization differences were observed in successful Analysis I students, but unsuccessful Analysis I students were more often left dominant. Two definitions of "success" yielded similar results. Included are 13 tables and 25 references. (DC)