Our system of research self-regulation, designed to provide internal checks and balances for those who participate in research involving human subjects, is under considerable stress. Much of this crisis has been caused by what we call mission creep, in which the workload of IRBs has expanded beyond their ability to handle effectively. Mission…

A discussion of resource allocation for scientific research identifies the ethical principles underlying the present debate and begins to construct a framework for evaluating various resource allocation proposals. The intent is to promote greater consideration of the link between ethics and science resource allocations. (Author/MSE)

The following administrative aspects of scientific experimentation with human subjects are discussed: the definition of human experimentation; the distinction between experimentation and treatment; investigator responsibility; documentation; the elements and principles of informed consent; and the administrator's role in establishing and…

Existing federal government policies and systems to protect against scientific misconduct in government-supported research projects are described, and additional considerations not covered in federal policy are enumerated. Misconduct inquiries and review procedures are outlined. Applicant and institutional responsibility and the role of prevention…

Describes organization and evaluation of 13 workshops at the University of Wisconsin-Madison providing professional development for clinical research support staff. Topics included ethics, protocol development, statistics, audits, and tips and tools for successful research. Evaluation indicated the workshops met educational goals but did not…

Purpose: The intention of this paper is to encourage debate among ethical researchers on this very important issue. Research necessary to underpin health education and health promotion is often controversial and often involves vulnerable populations such as young people and children. It is essential that the rights of these respondents are…

The evolution of research misconduct policies in universities is traced since the late 1970s. It is argued that research universities have been slow to accept responsibility for research misconduct, and they are urged to examine their research environments and place more emphasis on research ethics education. (MSE)

The integrity of research conducted in academic institutions should not be compromised in the conflict between the scientific community, public agencies, and legislators over oversight of federally funded projects. Integrity can be protected through prevention of abuse in researcher recruitment and training and through partnership between faculty…