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Sandman, Curt A.; Hetrick, William; Taylor, Derek V.; Chicz-DeMet, Aleksandra – American Journal on Mental Retardation, 1997
This study investigated whether blood plasma levels of pro-opiomelanocortin-derived (POMC) peptides, beta-endorphin-like activity, adrenocorticotrophic hormone, and adrenal cortisol immediately after self injurious behavior (SIB) episodes predicted subsequent response to an opiate blocker in 10 patients with mental retardation. Results suggest…
Descriptors: Behavior Disorders, Biochemistry, Drug Therapy, Medical Research
Peer reviewedDollfus, Sonia; And Others – Journal of Autism and Developmental Disorders, 1992
This study compared the clinical efficacy of a dopaminergic antagonist (amisulpride) and a dopaminergic agonist (bromocriptine) with 9 children (ages 4-13) with autism and probable severe mental retardation. The amisulpride acted preferentially on specific autism symptoms and the bromocriptine on motor hyperactivity and attention symptoms.…
Descriptors: Attention Control, Autism, Behavior Patterns, Children
