Comparison of cognitive processes in 23 individuals with Down's syndrome (DS) and 23 individuals of comparable mental handicap without Down's syndrome found that older (above 40 years) DS subjects had significantly poorer outcomes. The areas of speech rate, number finding, and expressive attention appeared to show the earliest signs of dementia of…

This paper reports on a 15-year follow-up of the linguistic and cognitive profile of a woman with standard trisomy 21 (Down syndrome). The follow-up found recent rapid deterioration in receptive and productive language skills. However, basic phonological and morphosyntactic skills are preserved. Her changing profile mirrors that found in aging…

This article reviews studies evaluating neurocognitive changes following organ transplantation in pediatric end-stage renal and liver disease. Findings suggest possible neurocognitive benefits associated with organ transplantation. Recommendations are made for methodological improvements in future research. (DB)

The conceptual frameworks of Thai children (n=48) related to causes of health and sickness were analyzed using the "Interview-about-Instances" and the "Conceptual Profile Inventory" techniques. The results indicate that Thai schoolchildren hold considerable personal knowledge about the causes of health and sickness that does…

Single word oral reading was systematically examined in a 6-year-old hyperlexic boy with mental retardation, attention deficit disorder, and hyperactivity. Reading performances were compared to those of normally developing readers and to those of patients with adult-onset alexias to test three hypotheses regarding the mechanisms of reading in…