The prevalence of Autism and other Autism Spectrum Disorders (ASDs) has increased dramatically in recent years. The criterion for a clinical diagnosis of Autism, however, is independent from the special education eligibility requirements for Autism services. While the DSM-IV-TR provides a nationally-accepted definition for Autism and ASD, under…

Through contributions from top leaders in Autism Spectrum Disorder (ASD), "Children and Youth with Autism Spectrum Disorder" examines the ASD research literature, discusses procedural implications, and makes recommendations for future practice and inquiry. It combines the most recent developments in established practices with newer and…

This review of magnetic resonance imaging (MRI) in autism addresses three questions: (1) what structural anomalies of the brain have been identified by MRI? (2) why are these collective findings inconclusive? and (3) where should neuroimaging research go from here? It is noted that the vast majority of MRI scans in autism are clinically…

In a field trial addressing revisions to autism criteria in the fourth edition of the Diagnostic and Statistical Manual (DSM-IV), information on 977 cases (454 with autism, 240 with "autistic-like" conditions, and 283 with nonpervasive developmental disabilities disorders) was rated. DSM-IV criteria were compared with the International…

This study compared four systems for diagnosis of autism (Diagnostic and Statistical Manuals of Mental Disorders III, III-R, and IV, and the International Classification of Disabilities-10) with 2 empirically derived taxa and 3 social subgroups (aloof, passive, and active but odd) in 194 preschool children with social impairment. Findings support…

Comparison of children (n=6) with either autism or Asperger syndrome (AS) and children (n=9) with neither condition found overall postural instability was significantly reduced in autistic children compared with both AS and normal children and confirms the existence of a visuo-postural detuning in autistic children. Results suggest a…

This paper examines the validity of Asperger syndrome as a condition apart from high-functioning autism. Potential differences between Asperger syndrome and autism is possible if both are strictly defined. The importance of genetic factors in Asperger syndrome is stressed. Research on the nosological validity of this condition and its relationship…

Seventeen patients with Asperger syndrome (AS) and a mean IQ of 97 were compared with a control group of 13 patients with normal intelligence or high-functioning autism. Results found that pedantic speech was common in the patients with AS and may help differentiate AS from high-functioning autism. (Author/CR)

This population study of eight California birth cohorts (1987-1994) examined the degree to which improvements in detection and changes in diagnosis contribute to the observed increase in autism prevalence from 5.8 to 14.9 per 10,000. A decreasing prevalence of mental retardation without autism suggests that improvements in detection and changes in…

The Autism Diagnostic Observation Schedule, a standardized protocol for observation of social and communicative behavior associated with autism, is described. Data on interrater reliability as well as test-retest reliability and discriminant validity are provided. (Author/DB)

This study of 102 individuals with autism found that the brainstem and cerebellum increased in size with age but were significantly smaller in autistic patients than in controls. Analysis of the speed of development suggests that brainstem and vermian abnormalities in autism were due to an early insult and hypoplasia rather than to progressive…

This paper reviewed the psychometric properties of the DSM-III-R (Diagnostic and Statistical Manual III, Revised) criteria for autism. Results indicated that the criteria had, on average, very good sensitivity but much lower specificity. It is concluded that the DSM-III-R criteria act more like screening criteria than diagnostic criteria.…

First offers a framework for thinking about diagnosis, prognosis, and treatment of autism. Then offers principles of program evaluation, describes components of appropriate early intervention programs, and offers guidelines for evaluating alternative treatments. (Author/DB)

The cytogenetic survey of 67 individuals previously identified as having mental retardation and autistic behaviors revealed only 1.5 percent with the fragile X chromosome. The finding suggests that most persons with fragile X syndrome do not have autistic behaviors severe enough to be identified as a secondary psychiatric diagnosis. (Author/DB)

This study found that motor impairment levels of 12 Asperger syndrome children and 9 high functioning autistic children (ages 7-17) did not differ. Intelligence level was negatively correlated with motor impairment. Fifty percent of Asperger children and 67% of children with autism showed a clinically significant level of motor impairment.…