This paper reviews the methodology in articles that have reported structural neuroimaging or neuropsychological data in adolescent patients with schizophrenia. Identification of methodological issues led to the finding that, at present, no conclusions can be made regarding the presence or absence of neuropsychologic dysfunction or structural…

This evaluation of thought disorders in 11 high functioning autistic young adults and older adolescents found poverty of speech, poor reality testing, perceptual distortions, and areas of cognitive slippage. In comparison with a schizophrenic reference group, autistic subjects demonstrated more poverty of speech and less illogic as well as similar…

The follow-up study examined 16 schizo-affective children after a mean of 16 years. In comparison to purely schizophrenic controls, subjects showed an increased incidence of affective psychoses, suicide in the ancestry, and more pre-morbidly well-adjusted personalities. The schizo-affective psychoses had mainly an acute-recurrent character.…

The demographic characteristics, life histories, and current placements of dually diagnosed elderly persons (n=27) was obtained by reviewing 132 case records of a Los Angeles regional center for developmentally disabled persons. Approximately 20 percent of the total sample were dually diagnosed and the most common mental health diagnosis was…

The high incidence of reported posttraumatic stress disorder (PTSD) among Vietnam veterans has prompted researchers to search for reliable assessment and treatment procedures for this disorder. Although some encouraging preliminary data on the use of the Minnesota Multiphasic Personality Inventory (MMPI) have been obtained, it is uncertain if this…

Examined effects of parental psychopathology and maltreatment on behavior of 102 children with mean ages of 9.75 years. Parental psychiatric status and maltreatment interacted significantly, so that offspring of schizophrenic parents from maltreating families showed increases in externalized behavior problems over time. (RJC)

Nine adult males with mental retardation resulting from Fragile X syndrome were compared to males with mental retardation of other etiology. Fragile X males showed a distinct psychological profile with more autistic features, more schizoid features, and more schizotypal features. These males were also more shy, more socially withdrawn, less…

This review of studies of early onset schizophrenia examines the nosological similarity between adult and early onset schizophrenia, differential diagnosis, treatment, and the extent to which children and adolescents diagnosed as having schizophrenia using adult criteria have the characteristic adult correlates. The paper discusses gender…

The validity of the schizophrenia subscale of the Psychopathology Instrument for Mentally Retarded Adults (PIMRA) was evaluated with 65 adults having mild to moderate mental retardation as well as either schizophrenia, depression, or no psychopathology. Univariate and multivariate analyses were conducted, as were interrater reliability analyses.…

This study found that the schizophrenia subscale of the Psychopathology Instrument for Mentally Retarded Adults was a valid quantitative measure of schizophrenia if one item was removed from the scale. Comparison with a nonretarded population indicated that mentally retarded patients had less delusions and more incoherence and flat affect. They…

A method for empirical classification of autistic and autisticlike children, based on behavior observations of 35 males and 11 females (ages 4-28 years) was examined. Factor and cluster analysis indicated four subtypes, characterized by perseverative thinking and play, motor disturbances, schizotypal/schizoid features, and anxiety and negativism.…