A lecture given in courses in applied pharmacokinetics at Wayne State University, Michigan, is presented. The definition of bioavailability is reviewed along with methods of calculation, bioequivalence, criteria for establishing bioequivalence of a new product, essentials of a bioequivalence study, and the relationship between bioequivalence and…

Discusses major uses of rats as experimental animals for studying health concerns, pointing out that their size, gestation, and histocompatibility make them useful in various studies. Topic areas addressed include aging, autoimmune disease, genetics, cancer, diabetes, hypertension, infection, reproduction, and behavior. (DH)

Defines biological engineering and discusses why it is needed. Lists some interesting areas of biological engineering. Presents a table of four phases of scientific disciplines. (YP)

Describes a computer simulation program which helps students learn the main biochemical tests and profiles for identifying medically important bacteria. Also discusses the advantages and applications of this type of approach. (ML)

Traces the history of using mice for medical research and discusses the benefits of using these animals for studies in bacteriology, virology, genetics (considering X-linked genetic homologies between mice and humans), molecular biology, immunology, hematology, immune response disorders, oncology, radiobiology, pharmacology, behavior genetics,…

Presents an introduction to the Biochemical and Biomedical Engineering program at Rice University. Describes the development of the academic and enhancement programs, including organizational structure and research project titles. (YP)

The advantages and justifications for using small animals in human-oriented research are reviewed. Some of the pitfalls of extrapolating animal-derived data to humans are discussed. Several specific problems with animal experimentation are highlighted. (CW)

Describes a college course designed to explicate the political dimensions of biomedical issues now emerging in American society. The course combines a rigorous overview of the technologies and the accompanying value changes which are producing these issues with a discussion of the problems being raised. (RM)

Describes the use of a short, fictional story about a woman's surgery to illustrate issues and promote discussion about biomedical ethics, particularly the issue of informed consent. Discussion connects the personal story with specific litigation, comparing legal requirements and ethical responsibility in physician-patient communication. (MSE)

Described is a capstone experience for undergraduate biomedical engineering students in which student teams work with children and adults with cerebral palsy to produce devices that make their lives easier or more enjoyable. The collaborative approach, benefits to the clients, and evaluation of the projects are discussed. (CW)

Universities are compounding the problems created by faculty entrepreneurship by gaining an unprecedented financial interest in the prosperity of the biomedical industry. This interferes with the institutions' other functions of critiquing social policy, explaining technical matters, and performing research for publicly decided goals. The…

Describes an undergraduate research program for minority students. The program and eight objectives of the first course of the program, "Introduction to Research," are presented. Some strengths and weaknesses of the course are considered. (YP)

An examination of the changes over a ten-year period (from 1972 to 1982) in the number, distribution, and characteristics of Ph.D. faculty of clinical departments of medical schools is provided in this report. Trends in the training and research involvements of this group are stated with special emphasis on an analysis of the factors associated…

The purpose of this guide, developed by the Association of American Medical Colleges group on Graduate Research, Education, and Training (GREAT), is to outline a model process by which graduate programs can measure program success and that can be adapted to particular circumstances and priorities. The first sections of the guide examine the…

Designed to provide assistance in the assessment of the need for biomedical and behavioral research personnel, this report presents research findings related to specific medical careers. The review includes an examination of the system under which biomedical and behavioral scientists are trained for research careers and the United States…