Title IV of the Higher Education Act (HEA; P.L. 89-329), as amended, authorizes programs that provide financial assistance to students to pursue postsecondary education at eligible institutions of higher education (IHEs). In academic year (AY) 2020-2021 (July 1, 2020-June 30, 2021), 6,063 domestic institutions had written agreements with the Department of Education (ED) that allow them to participate in any of the Title IV federal student financial assistance programs. To receive Title IV assistance, students must attend an institution that participates in the Title IV programs. This report provides a general overview of HEA Title IV institutional eligibility requirements, as well as some institutional Title IV student aid program participation requirements. It first describes general eligibility criteria at both the institutional and programmatic level and then, in more detail, the program integrity triad. Next, it discusses several issues that are closely related to institutional eligibility: Program Participation Agreements, including the 90/10 rule and campus safety policies and crime reporting required under the Clery Act, and distance education.