College plays an increasingly critical role in a person's employment and long-term success. However, in seeking employment, college students with disabilities may encounter distinctive employment contexts compared to their peers without disabilities. This research brief provides an overview of the employment landscape for individuals with disabilities and career development considerations for college students with disabilities. Additionally, this brief offers recommendations to institutions regarding personalized career development for targeted student groups and strategies for improved support to students as they plan their career trajectories. These include: 1) developing stronger partnerships between offices of disability resources and career services; 2) implementing universal design for career development; and 3) capitalizing on technology to expand access to disability-focused career services. Finally, the limits to what is currently known about post-college employment for this group of students are discussed. (Contains two tables.)