This project for large-group, problem-based learning at Kansas State University College of Veterinary Medicine developed 47 case-based videotapes that are used to model clinical conditions and also involved veterinary practitioners to formulate true practice cases into student learning opportunities. Problem-oriented, computer-assisted diagnostic programs were also modified to help veterinary students increase their skills in differential diagnosis. The study was also successful in evaluating the neurological problem-space of third-year veterinary students, both in initial groups and subsequently as individuals, distinguishing skilled from novice diagnostic reasoning. The study found that problem-based learning fostered significant advantages and increased student confidence and in-depth learning. Disadvantages included reduced breadth of learning, considerable time requirements, and significant ambiguity. Twelve of the tapes are being used at two other veterinary schools. Sections of the report are devoted to an extensive list of the tapes produced and in production; a bibliography of materials produced by the project, in addition to the project overview, purpose, background and origins, and detailed evaluations and findings. Appendices include "Evaluator Analysis of Interviews" (John Pickrell, Susan Santos, David Balk) undertaken with 35 veterinary medicine students, predominantly in their junior and senior years. (Contains 142 references.) (SW)