This guide, intended for college and university presidents and governing board members who are committed to the elimination of drug and alcohol abuse on their campuses, provides a description of the extent of alcohol and other drug use and abuse on campuses and recommends five intervention strategies for these institutions to use. The strategies include (1) developing clear alcohol and other drug policies; (2) enforcing alcohol and other drug regulations; (3) providing alcohol and other drug education programs; (4) insuring intervention and referral for treatment of students, faculty, and staff; and (5) assessing alcohol and other drug attitudes and behaviors, and the impact of education, prevention, and treatment programs. For each intervention, very specific recommendations are given on what presidents and governing board members must do to eliminate drug and alcohol abuse. Appended are a set of guidelines for beverage alcohol marketing by the Interassociation Task Force on Campus Alcohol Policy Issues and the standards of the Network of Colleges and Universities Committed to the Elimination of Drug and Alcohol Abuse. Contains nine references. (Author/GLR)