Past research has indicated an association between parents' beliefs and adolescent children's self-perceptions of ability and has shown the importance of accounting for parents' gender-stereotyped beliefs when examining boys' and girls' self-perceptions of math-science ability. The current study extends these findings by examining the longitudinal relations between mothers' earlier gender stereotypes and perceptions and adolescents' later math-science achievement beliefs and career choices. As predicted, mothers' earlier perceptions of their adolescents' abilities were related to adolescents' math-science self-efficacy 2 years after high school, with adolescents' self-perceptions of math ability during 10th grade mediating the relation with mothers' perceptions. Moreover, mothers' earlier predictions of their children's abilities to succeed in math careers were significantly related to later career choices.