This guide was created for school administrators, parents, teachers, and community groups interested in developing effective alcohol and drug abuse prevention programs for elementary and secondary schools. A comprehensive approach to school-based alcohol and drug prevention is described and various prevention activities which have been selected by the National Highway Traffic Safety Administration are related to highway safety issues. Each of the five chapters of this guide focuses on a different but related approach to alcohol and drug education. Classroom education and teacher training are discussed in Chapter 1, which contains curricula and related materials for a basic alcohol and drug education program, "Here's Looking at You Two," and for drinking and driving programs which can be used in conjunction with ongoing highway safety/driver education programs. The need for parent education is addressed in Chapter 2, which describes methods by which parents can support and reinforce the effectiveness of classroom alcohol and drug education. "The Family Interaction Program" is highlighted in this section, with a discussion of program goals, special features, and activities. Community approaches are described in Chapter 3, including the Sumner Tobacco and Alcohol Risk Reduction Project (STARR) of Pierce County, Washington and a variety of programs designed to involve community organizations and institutions in school-based prevention efforts. In Chapter 4 two types of early intervention approaches for students with alcohol or drug problems are described, the "Natural Helpers Program" and "The Student Assistance Program." The need for realistic school policies regarding alcohol and drug use is stressed in Chapter 5 and guidelines for policy development are provided. Sample materials and forms from each of the model prevention programs are included in a colored resource pages section at the end of each chapter. (NRB)