Since the 2016 presidential campaign, for better or worse, the general public and media have placed rural America in the national spotlight. While the election placed an important spotlight on the lives, challenges, and strengths of people living in rural communities, the spotlight came with the perpetuation of myths of rural America (e.g., people from rural communities are white, ignoring the lives of rural people of color). The national attention on rural America has also elevated the stories of rural students as they navigate their pathways to and through postsecondary education (or not); these stories have been documented in the national media. The purpose of this research to practice brief is to serve as a resource for professionals who serve students as they make choices about pursuing postsecondary education. This report begins with a brief overview of the political and social contexts that shape rural schools and districts. The report then provides an overview of the factors that constrain and promote college access and enrollment for rural students. It concludes with strategies and recommendations for counseling professionals, college access and preparation program professionals, and higher education enrollment management and admission professionals to enhance college access and enrollment for rural students.