While Alberta enjoys proven high, world-class results in student achievement, raising high school completion rates is one of the top priorities in improving the provincial education system. The 2011-12 targeted high school completion rate is 82% five years after entering Grade 10--a 2.5% increase from the current average rate of 79.5%. The purpose of this study is to contribute to the Alberta High School Completion Initiative by conducting a concurrent, comprehensive large-scale analysis of presently available provincial data (e.g., Corporate Data Warehouse) and other data sources (e.g., Statistics Canada), in order to better understand the local contexts and factors pertinent to high school completion and inform policies directed at helping students complete high school. The findings presented in this report are based on the cohort of 32,721 Alberta students who started Grade 3 in 1995-96 and entered Grade 10 in 2002-03. The report has two major parts. The first portion reports the results of bivariate analysis of the associations between high school completion and each of the identified factors that may contribute to high school completion (potential predictors). Bivariate analysis involves examination of the association between high school completion and each individual predictor variable. The second portion of the report discusses the results of an analysis of the examined predictors by means of multiple logistic regression. Multiple regression modeling accounts for the effects of all included predictors and hence, provides an integrated picture of the key predictors. The findings outlined in this report have clear practical implications for cross-disciplinary research, focused policy development and interagency interventions at a school, district and system level. (Contains 2 tables, 31 figures, and 8 footnotes.)