This guide provides information to persons interested in establishing a work-at-home program, specifically those in clerical or support staff positions who use modern automated office equipment. The text is divided into two sections. The Home Worker section provides a summary of the At Home in the Office Project, personality characteristics believed to be related to successful home work programs, characteristics of work that seem to be suited for working at home, and laws and agencies that affect the home worker. The Online Lines section supplies information to help home workers select appropriate hardware and software for the basic work station and optional equipment to add to the basic design. Other topics include defining a work space, selecting appropriate furnishings, arranging the home work station, and telecommuting and its suitability for home workers. Five exercises are provided to help home workers evaluate the home work option more precisely. They cover assessing the suitability of one's personality and job to home work; assessing software needs; comparing hardware, software, and vendors; evaluating available software packages; and designing a home work space. Two other exercises help to figure the start-up costs and to ascertain the feasibility of telecommuting. A simulation of a typical home worker's day follows. A glossary, entitled "New Language for the Office," is attached. (YLB)