ACT has been investigating issues and supports related to high school students' mental health even before the COVID-19 pandemic. ACT researchers expanded on prior research by asking students to indicate, near the beginning of the new 2020-2021 school year, their perceptions of how well their school was supporting their mental health and the extent to which daily life experiences during the pandemic had helped or hurt their mental health. A random sample of 2,291 high school students who sat for the 2020 October National ACT® test participated in an online survey. These students provided insights regarding their learning context, the mental health support they received, and whether they had experienced additional stressors during the pandemic, particularly whether they had academic concerns this school year or concerns regarding their college preparedness. Because students varied in whether their schools were offering in-person, virtual, or hybrid learning (or had changed between these three learning models during the current school year), the study further examined whether differences in learning contexts shaped the mental health support that students received from their schools or their concerns about academic preparedness. This latest study, which includes the voices of students themselves, will be useful to policymakers and school system administrators as they analyze and apply Centers for Disease Control and Prevention (CDC) guidelines in determining when and how to safely return students to the classroom.