The "Talent Development Middle Grades Program" is a comprehensive reform model that transforms the structure and curriculum of large urban middle schools with the aim of improving student achievement and raising teacher and student expectations. Key features of the "Talent Development Middle Grades Program" include small learning communities, an evidence-based curriculum tied to standards, the use of teacher teams, professional development and support for teachers, and school-family-community connections. This review focuses on the effects of the "Talent Development Middle Grades Program" on student reading outcomes. "Student Team Literature" is the literacy component of the "Talent Development Middle Grades Program," and is therefore relevant to this review in the Adolescent Literacy topic area. "Student Team Literature" is a reading and English language arts curriculum for middle school students that utilizes cooperative learning activities, high-interest reading materials, and explicit instruction to teach reading strategies, comprehension skills, and fluency in reading and writing. It offers integrated reading, writing, and language arts instruction and a writing process approach to language arts. As part of the program, students work in groups, and activities follow a regular cycle that involves teacher presentation, team practice, independent practice, peer preassessment, and individual assessments that form the basis for team scores. The cooperative learning teams are intended to engage students in academic interactions and create a motivating environment. The What Works Clearinghouse (WWC) identified one study of the "Talent Development Middle Grades Program" that both falls within the scope of the Adolescent Literacy topic area and meets WWC evidence standards with reservations. The study included adolescent readers from grades 7 and 8 in 29 urban middle schools in the Northeast. The WWC considers the extent of evidence for the "Talent Development Middle Grades Program" on the reading performance of adolescent readers to be small for one outcome domain: comprehension. The "Talent Development Middle Grades Program" was found to have potentially positive effects on comprehension for adolescent readers. Appended are: (1) Appendix A: Research details for Herlihy & Kemple, 2004; (2) Appendix B: Outcome measures for the comprehension domain; (3) Appendix C: Findings included in the rating for the comprehension domain; (4) Appendix D: Summary of additional intermediate findings for the comprehension domain; and (5) WWC Rating Criteria. A glossary of terms is included. (Contains 4 tables, 8 endnotes and 3 additional sources.)