Background: Autism spectrum disorder (ASD) is a multifactorial, pervasive, neurodevelopmental disorder, of which intestinal symptoms collectively represent one of the most common comorbidities. Methods: In this study, 1,222 children with ASD and 1,206 typically developing (TD) children aged 2-7 years were enrolled from 13 cities in China. Physical…

Objective: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders with underlying pathogenesis and etiological factors not fully understood. We assumed that galectin-3, which is also linked with inflammatory responses, may be central to the ethiopathogenesis of ASD. Method: The current study consisted of 33 psychotropic…

Introduction: A previous study has evaluated the association between serum tumour necrosis factor-like weak apoptosis inducer (TWEAK) levels and autism spectrum disorder (ASD). In line with this investigation, the present study aimed to measure serum TWEAK levels to determine whether their eventual alteration might have etiopathogenetic…

Children with autism spectrum disorder (ASD) have difficulties with emotion recognition and a number of interventions have been designed to address this problem. The purpose of this study was to examine the effects of video-based intervention (The Transporters) on emotion recognition in four children (aged 4-8 years old) with ASD who have limited…

Purpose: Children with developmental language disorder (DLD) have well-documented verb learning difficulties. In this study, we asked whether the inclusion of retrieval practice during the learning period would facilitate these children's verb learning relative to a similar procedure that provided no retrieval opportunities. Method: Eleven…

We examined adult behavioral skills training (BST) for home-based therapeutic support staff (TSS) using a naturalistic developmental behavioral intervention (NDBI) with young children with Autism Spectrum Disorder (ASD) derived from Project ImPACT. We taught three TSS to use interactive strategies with online modules, in-vivo training, and ongoing…

Objective: This study examined the relationship between sensory processing (SP) differences and behavioral problems in children with autism spectrum disorder (ASD). We also investigated whether audiological test results could objectively detect auditory processing differences. Method: Forty-six children with ASD, ages 3-9 years, were enrolled in…

Several robot-mediated therapies have been implemented for diagnosis and improvement of communication skills in children with Autism Spectrum Disorder. The proposed research uses an existing model i.e., Multi-robot-mediated Intervention System (MRIS) in combination with Hidden Markov Model (HMM) to develop an infrastructure for categorizing the…

Children with autism spectrum disorders (ASD) are at greater risk for reading difficulties, and for many children, the promotion of reading fluency is an appropriate intervention goal. However, few studies have specifically examined the use of repeated reading (RR) with young children with ASD. The present study used a RR intervention in…

Several studies have shown the efficacy and effectiveness of the Early Start Denver Model, both in university and in community-based settings. However, a limited number of studies have investigated predictors of outcomes. In this study, we examined outcomes in 32 children diagnosed with autism spectrum disorder after 1 year of community-based…

Given the importance of parent involvement and parent-implemented interventions in achieving maximum child outcomes, practitioners need valid measures to assess and monitor family outcomes in developing and delivering effective and sustainable interventions. This study examined the structure of the Family Outcomes Survey, Form A, using a sample of…

The Childhood Autism Rating Scale (CARS), (Schopler et al. in J Autism Dev Disord 10(1):91-103, 1980) is a 15-item observation-based rating scale that yields a total score reflective of autism symptom severity. This study investigated the factor structure of the CARS in a sample of 2-year-old children with DSM-IV-TR (American Psychiatric…

The present study examined the relationships between the standardized applied behavior analysis (ABA) direct assessment, the PEAK Comprehensive Assessment (PCA), and established assessments commonly used in educational and clinical settings, including the Childhood Autism Rating Scale - Third Edition (CARS-3), the PDD Behavior Inventory (PDDBI),…

This study examined maintenance of treatment effects in a culturally tailored parent education program for Latinx families of children with autism spectrum disorder using a behavior maintenance framework. In a two-site randomized waitlist-control study, we compared differences in parent and child outcomes across three timepoints using linear mixed…

Children with autism spectrum disorder (ASD) present with social skills difficulties, which can create barriers for them to develop friendships with their peers. Playdates are a common way that young children practice play and friendship skills in home and community environments. Few studies have trained parents to embed social skills instruction…