Faecal transplantation . . . and other stories
BMJ 2023; 380 doi: https://doi.org/10.1136/bmj.p69 (Published 19 January 2023) Cite this as: BMJ 2023;380:p69
Faecal transplantation for C difficile
A randomised trial of faecal microbiota transplantation for the treatment of a first or second infection with Clostridioides difficile was stopped early after an interim analysis. The primary outcome, resolution of diarrhoea at week eight, had been achieved in 19 of 21 patients in the faecal microbiota transplantation group compared with only seven of 21 patients in the placebo group. All patients had previously been treated with vancomycin for 10 days (Lancet Gastroenterol Hepatol doi:10.1016/S2468-1253(22)00276-X).
Asymptomatic orthostatic hypotension
Orthostatic hypotension, defined as a drop in systolic blood pressure of ≥ 20 mm Hg or in diastolic pressure of ≥ 10 mm Hg after standing, affected more than one in 10 participants …
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