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Refractive changes in children in the Chicago area during the COVID-19 pandemic: a retrospective observational study (see page XXX)
Statistically significant worsening of myopia progression was observed in children after COVID-19 home confinement. Elementary school age children demonstrated the greatest increase in myopia prevalence. Low myopia patients demonstrated the greatest change in mean spherical equivalent.
Semiautomated measures of foveal immaturity from handheld swept-source optical coherence tomography are associated with retinopathy of prematurity severity (see page XXX)
Using handheld swept source optical coherence tomography, markers of foveal immaturity, including shallower foveal angle, higher inner retinal fovea/parafovea ratio, and larger retinal cross-sectional area, were associated with more severe retinopathy of prematurity.
In vivo lacrimal gland imaging artefact assessment based on swept-source optical coherence tomography for dry eye disease (see page XXX)
This study proposes a standard framework to assess quality of OCT images of the lacrimal gland, highlighting the impact of dry eye disease and intraocular pressure on image quality.
Outcomes of staged conjunctival flap and corneal transplantation for infectious keratitis resistant to medical treatment (see page XXX)
Conjunctival flap surgery followed by staged keratoplasty represents an alternative therapeutic approach to avoid high risk keratoplasty “a chaud” in cases of severe infectious keratitis.
Comparison of clinical outcomes between different combinations of hybrid multifocal, extended-depth-of-focus and enhanced monofocal intraocular lenses (see page XXX)
Blending enhanced monofocal or extended-depth-of-focus IOLs with trifocal IOLs improves near vision with fewer photic phenomena. However, the same trifocal IOLs implanted in both eyes yield superior reading speed in near vision and better contrast sensitivity outcomes.
Earliest location of glaucomatous retinal nerve fibre layer damage is determined by intact baseline RNFL thickness profile (see page XXX)
This longitudinal study provides evidence that the most vulnerable site of axonal injury in glaucoma is strongly associated with the intact baseline retinal nerve fibre layer thickness profile.
Nyctohemeral effects of topical beta-adrenoceptor blocking agents measured with an intraocular telemetry sensor (see page XXX)
This study evaluated nyctohemeral effects of topical β-blocking (βB) agents using telemetry. Combinations of βB-prostaglandin analogues had more pronounced effects on lowering 24 hours IOP fluctuations than βB-carbonic anhydrase inhibitors and βBs alone.
Comparison of baseline clinical characteristics and patterns of visual field defects between high-tension and normal-tension glaucoma (see page XXX)
Normal-tension glaucoma exhibited greater asymmetry in the visual field compared with high-tension glaucoma, with daytime intraocular pressure fluctuations linked to the asymmetry in normal-tension glaucoma.
Clinical characteristics and optical coherence tomography features of ocular toxoplasmosis in HIV-positive patients: report 1 (see page XXX)
This study of ocular toxoplasmosis (OT) in HIV patients establishes OT presentation as bilateral, large, multifocal retinitis with amoeboid extensions and horizontal spread. Anterior uveitis, RPE elevation and choroidal inflammation are the secondary changes.
Short-term intraocular pressure changes after intravitreal aflibercept 2 mg, aflibercept 8 mg and faricimab: a prospective, comparative study (see page XXX)
Intravitreal aflibercept 8 mg and faricimab cause significant transient intraocular pressure (IOP) spikes, which normalise within 15 min. Faricimab induced a smaller early IOP increase compared with aflibercept, but the difference declined after 5 min.
Outlier ophthalmologists in the treatment of neovascular age-related macular degeneration with intravitreal therapy (see page XXX)
Eyes with neovascular age-related macular degeneration treated by low outlier practitioners had fewer injections, fewer visits and longer interval of injections than eyes treated by high outliers and non-outliers. Eyes treated by low outliers had a significantly higher proportion of visits at which CNV was active than the non-outliers. Detecting outlier ophthalmologists is the first step in a quality assurance process.
Colour vision deficiency is associated with increased prevalence of amblyopia, strabismus and ametropia: a large population study (see page XXX)
This large population study shows that ametropia, strabismus and amblyopia were more common in individuals with colour vision deficiency. Screening in childhood for colour vision deficiency could help in avoiding preventable vision loss.
Metabolomic signature of retinal ageing, polygenetic susceptibility, and major health outcomes (see page XXX)
This study incorporatng participants from the UK Biobank and the Guangzhou Diabetes Eye Study (GDES) demonstrated that a higher retinal ageing metabolic signature is associated with higher risks of 12 serious health conditions.
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Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.