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A case of hypothyroidism in infancy
  1. Maryam Sahibqran1,2,
  2. Angela Katrina Lucas-Herald2,
  3. Ruth McGowan2,3,
  4. M Guftar Shaikh1,2
  1. 1Paediatric Endocrinology, Royal Hospital for Children, Glasgow, UK
  2. 2Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
  3. 3Clinical Genetics, Royal Hospital for Children Glasgow, Glasgow, UK
  1. Correspondence to Dr M Guftar Shaikh; guftar.shaikh2{at}nhs.scot

https://doi.org/10.1136/archdischild-2024-327924

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    Patient X was investigated at 6 months of age for weight gain. She was born on the 9th centile at 35 weeks and was between the 25th and 50th centile at 6 months, with length below the 0.4th centile (see growth chart). She had no obvious dysmorphic features or family history of note. Her newborn screening thyroid-stimulating hormone (TSH) result was normal. Current thyroid function tests (TFTs) at 6 months of age are shown below:

    TSH: 15.98 (reference range 0.35–5.00) mU/L

    Free T4: 8.1 (reference range 9.0–21.0) pmol/L

    Thyroid antibody testing: Negative

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    1. On assessment in clinic you notice that her weight has further increased by 1.5 kg in 4 weeks (see growth chart in figure 1).

    Figure 1

    Growth chart of child. Dots, weight at chronological age; x, weight at corrected gestation (5 weeks preterm). …

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    Footnotes

    • X @lucas_herald

    • Contributors All authors contributed equally. GS is the guarantor.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.