Attracting K–12 students to pursue careers in science, technology, engineering, and mathematics (STEM) is viewed as a critical element for benefiting both the economy and society. This paper describes an outreach program, conducted in a Brooklyn, NY, USA, public middle school, aimed at educating students in mechatronics, biology, and bioinspiration. The program is designed to foster student interest in STEM subjects, especially engineering-related concepts, by actively demonstrating their application in solving tangible real-world problems. It consists of a series of lectures and practical activities that culminate with a hands-on bioinspiration-based event at the New York Aquarium. Survey results show that students who participated in the program have a better understanding of the relationship between engineering and nature, demonstrate improved knowledge of select STEM topics, and are more interested in pursuing STEM careers.