You are here

  • Home
  • Archive
  • Volume 13, Issue 11
  • Interventions to treat patients with blood blister-like aneurysms of the internal carotid artery: a protocol for a network meta-analysis

Article Text

Article menu
Neurology
Protocol
Interventions to treat patients with blood blister-like aneurysms of the internal carotid artery: a protocol for a network meta-analysis
  1. Yujian Li1,
  2. Xiang Yang1,
  3. Huiqing Zhou2,
  4. Hao Li1,
  5. Jun Zheng1,
  6. Li Li3,
  7. Xuhui Hui1
  1. 1Department of Neurosurgery, Sichuan University West China Hospital, Chengdu, China
  2. 2Department of Intensive Care Unit, Fourth People’s Hospital of Sichuan Province, Chengdu, China
  3. 3Department of Outpatient, West China Hospital of Sichuan University, Chengdu, China
  1. Correspondence to Xuhui Hui; hxhmed0514@163.com; Li Li; llmed0514@163.com

Abstract

Introduction Blood blister-like aneurysm (BBA) is a special type of intracranial aneurysm with relatively low morbidity and high mortality. Various microsurgical techniques and endovascular approaches have been reported, but the optimal management remains controversial. For a better understanding of the treatment of BBA patients, a network meta-analysis that comprehensively compares the effects of different therapies is necessary.

Methods and analysis This protocol has been reported following the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols. Related studies in the following databases will be searched until November 2022: PubMed, Embase, Scopus, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), VIP and Wanfang. Randomised controlled trials (RCTs) and non-randomised studies comparing at least two different interventions in BBA patients will be included. Quality assessment will be conducted using Cochrane Collaboration’s tool or Newcastle-Ottawa Scale based on their study designs. The primary outcome is the composite of the incidences of intraoperative bleeding, postoperative bleeding and postoperative recurrence. The secondary outcome is an unfavourable functional outcome. Pairwise and network meta-analyses will be conducted using STATA V.14 (StataCorp, College Station, Texas, USA). Mean ranks and the surface under the cumulative ranking curve will be used to evaluate every intervention. Statistical inconsistency assessment, subgroup analysis, sensitivity analysis and publication bias assessment will be performed.

Ethics and dissemination Ethics approval is not necessary because this study will be based on publications. The results of this study will be published in a peer-reviewed journal.

PROSPERO registration number CRD42022383699.

  • neurosurgery
  • protocols & guidelines
  • statistics & research methods
http://creativecommons.org/licenses/by-nc/4.0/

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

https://doi.org/10.1136/bmjopen-2022-071415

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

View Full Text

Supplementary materials

  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

Footnotes

  • YL and XY are joint first authors.

  • YL and XY contributed equally.

  • LL and XH contributed equally.

  • Contributors YL, JZ and XY are responsible for the conception of the study. YL, JZ, HZ and HL designed this protocol. YL, JZ and XY tested the feasibility of this protocol. YL and XY wrote the original draft. XH, LL, JZ and HL revised the draft.

  • Funding This work was supported by the National Natural Science Foundation of China grant number 81801186, Science and Technology Department of Sichuan Provence grant number 2020YFQ0009 and Outstanding Subject Development 135 Project of West China Hospital, Sichuan University grant number ZY2016102.

  • Competing interests None declared.

  • Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.