You are here

  • Home
  • Archive
  • Volume 12, Issue 9
  • Determinants of responsiveness to multidisciplinary chronic pain management interventions: protocol for a systematic review and meta-analysis

Article Text

Article menu
Anaesthesia
Protocol
Determinants of responsiveness to multidisciplinary chronic pain management interventions: protocol for a systematic review and meta-analysis
  1. Maiju Marttinen1,
  2. Petteri Oura2,3,
  3. Merja Huttunen4,
  4. Pekka Vartiainen5,
  5. Markus Paananen2,6
  1. 1The Finnish Center for Pediatric and Adolescent Pain Management and Research, New Children’s Hospital, Helsinki University Hospital, Helsinki University Central Hospital, Helsinki, Finland
  2. 2Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland
  3. 3Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
  4. 4Department of Anesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital, Helsinki, Finland
  5. 5Department of Paediatrics, Päijät-Häme Central Hospital, Lahti, Finland
  6. 6City of Espoo Health Services, Espoo, Finland
  1. Correspondence to Dr Maiju Marttinen; maiju.marttinen{at}helsinki.fi

Abstract

Introduction The current manuscript presents a protocol for a systematic review and meta-analysis of the evidence regarding the determinants of responsiveness to multidisciplinary management of chronic pain, with pain intensity, pain-related interference, physical functioning and health-related quality of life as the main outcomes, with consideration to multiple secondary outcomes.

Methods and analysis To identify relevant studies, the Ovid MEDLINE, PubMed, Ovid PsycINFO, EBSCO CINAHL and Scopus databases will be searched for all studies exploring factors associated with responsiveness to multidisciplinary pain management from study inception to the present. Cohorts, case–control studies and randomised controlled trials will be included. Independent screening for eligible studies will be completed by a total of four researchers using defined criteria. Data extraction will be executed by two researchers. Study heterogeneity will be estimated using the I2 index. A meta-analysis will be performed using random effects models. Publication bias will be evaluated by means of funnel plots and Egger’s test.

Ethics and dissemination The proposed study does not involve collection of primary data. Therefore, no ethical approval is required. The results of the systematic review and meta-analysis will be presented in a peer-reviewed journal and at conferences.

PROSPERO registration number CRD42021236424.

  • Pain management
  • Rehabilitation medicine
  • GENERAL MEDICINE (see Internal Medicine)
http://creativecommons.org/licenses/by-nc/4.0/

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

https://doi.org/10.1136/bmjopen-2021-057481

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Supplementary materials

    • Supplementary Data

      This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

    Footnotes

    • Contributors MM, MH and MP designed the study. PO and PV contributed to the statistical designing. MM and PO prepared the manuscript. All authors read and approved the final manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.